We provide prokaryotic RNA sequencing, eukaryotic RNA sequencing, viral RNA sequencing, microbial iso-seq, and metatranscriptomics for microbial transcriptomics and metatranscriptomics studies. Next-generation sequencing (NGS) and long-read sequencing have allowed us to better understand the functions of microorganisms through microbial expression profiling. NGS produces higher coverage and is more accurate than long-read sequencing methods. However, long-read sequencing technologies including PacBio SMRT sequencing and Oxford nanopore sequencing have become increasingly popular due to their capacities in determining full-length transcripts and in de novo assembly.
Microbial transcriptomics holds promise in uncovering novel ways to treat disease and improve human health. For example, bacterial expression profiling has identified major shifts in the expression of metabolic pathways related to disease pathogenesis in human microbiome. Microbial transcriptomics is also important for predicting resistance to specific antibiotics, exploring host-pathogen immune interaction, and tracking disease progression.
Request a Quote
