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Microbial Bioinformatics

Microbial Bioinformatics

Overview

In almost all environments, microorganisms are prevalent. For industrial fermentation, medical health, and bioengineering, are significant. Genomic sequencing gives us an influential perspective into the microbial world's genetic makeup. To help our customers comprehend how microbes affect humans and the environment and then better make use of them. CD Genomics offers a wide array of microbial genomics alternatives.

Our Advantages:

Professional, comprehensive, and customized bioinformatics analysis pipeline.
Standardized laboratory methods and strict quality control.
Advanced genomics solutions and genome-based analysis.
State-of-the-art sequencing platforms including next- and third- generation sequencing.

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Introduction to Our Microbial Bioinformatics Services

Knowing the structure and qualities of bacterial diversity has been facilitated by the advancement of genomic technology. Existing findings suggest that under standard laboratory circumstances, less than 1 percent of microorganisms can develop alone. Microbial genomics, on the other hand, gives a more comprehensive pattern of the community's organisms and can define the population characteristics faster. Additionally, using genomics innovations, new species could be classified. CD Genomics, coupled with skilled, great support, offers you top technological abilities and scientific expertise and achieves High-Resolution Microbial Analysis, granting you all you need for high-quality, actionable information.

Applications

Human Microbiome

In order to expose the interactions between microorganisms and human health, metagenomics and 16S rRNA sequencing can be utilized to define human microbiome at major body locations. In the research of the human microbiome, the advancement of metagenomic sequencing using the next generation sequencing (NGS) technology has made remarkable improvement.

Environmental Microbiome

Environmental microbiology, such as its mechanisms and interactions, is described as the analysis of microorganisms found in the environment. Air, soil, and aquatic systems, extreme environments, and even astrobiology contain this field of research.

Microbial Innovations

Many advancements in the microbial field have been supported by the implementation of genomics technology, such as drug discovery and development. The development of a large amount of microbial genomics sequencing data not only encourages the improvement of basic biology but also enhances the diagnosis and typing of diseases, drug delivery, the identification of pathogens for virulence and antibiotic resistance, as well as the emergence of new vaccines and therapies. NGS also speeds up agricultural and industrial progress in addition to medicine by giving advanced microbial products.

Bioinformatic Analyses

Analysis Contents	Details
Functional metagenomics	New functional genes, microbial processes, antibiotic resistance genes, and functional abnormalities of microbial groups can be recognized by functional metagenomics. And the interaction and co-evolution between the microbiota and hosts can also be determined.
High-throughput sequencing	To define, categorize and quantify microorganisms in the environment, high-throughput sequencing technologies can be employed, thus exposing the magnitude of bacterial population and biosynthetic processes and increasing the progress of novel microbial products and by-products.
Heatmap	Offers simulation of information for multiple tasks, such as microarray and RNA-Seq data differential expression analyses.
Multi-Omics Integration Analysis	Providing data on biomolecules from various elements seems to be promising to comprehend complex biology systematically and holistically. It can be utilized for subtyping diseases, predicting biomarkers, and deducing data insights.
Annotation	Assess the gene locations and all the coding areas in a genome and evaluate what those genes do.
Biodiversity Informatics	Data on biodiversity, such as taxonomy, biogeography or ecology, is introduced to informatics methods.

Sample requirements

1. Specimens from human, animal, natural and industrial environments, as well as DNA and PCR products.
2. 1.8 < OD_260/280 < 2.0, OD_260/230 ≥ 1.8, no degradation or contamination.
3. Illumina platform: prokaryotic/eukaryotic DNA/cDNA amount ≥ 2 μg, viral DNA/cDNA amount ≥ 1 ug
4. PacBio platform: bacterial DNA amount ≥ 5 μg, fungal DNA amount ≥ 10 μg

Deliverables: Raw sequencing data (FASTQ), trimmed and stitched sequences, quality-control dashboard, statistic data, and your designated bioinformatics report.

* For Research Use Only. Not for use in diagnostic procedures or other clinical purposes.