Microorganisms can be applied as production strain or food ingredient when they are stable and functional under certain conditions. For example, probiotic bacteria need to be resistant to gastric acid in the stomach and intestines. To ensure the consistent performance of microbial strains, it is necessary to investigate which genes are expressed in a desired physiological environment. Our gene expression analysis service enables the identification of phenotypic differences at molecular level, provides insight into the role of differential gene expression in microbial bio-processes, and help to discover novel genes and mRNA isoforms.
Metatranscriptomic analyses measure the expression of multiple genes and functions at once by detecting and quantitating mRNA transcripts. Metatranscriptomics explores the functional diversity of microbial community in different habitats, as well as to examine microbial response in an altered environment. Metatranscriptomics simultaneously investigates the structural and functional diversity of a certain microbial community. We also apply RNA-seq approach to detect, quantitate and compare mRNA transcript levels of a certain microbial strain under various conditions. We offer both microbial RNA-seq based on NGS and full-length, direct RNA sequencing based on PacBio or Oxford nanopore platform for gene expression analysis.
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