Long Read Sequencing for Climate and Environment Change

Rapid global climate change is posing a major threat to biodiversity. Assessing population vulnerability and adaptive capacity under climate change is critical for developing conservation and mitigation strategies. As a leading company with extensive experience in genomics research, CD Genomics provides long read sequencing solutions to help you obtain the detailed information you need to assess a species' ability to adapt to ecological and environmental changes.

Introduction to Species Adaptations to Climate and Environmental Changes

Observed rapid climate change is expected to profoundly affect species distribution and diversity and is recognized as one of the major causes of biodiversity decline and/or loss over the next century. Evidence of climate-induced localized extinctions is widespread among plant and animal species. Spatial projections of future climate change impacts rely heavily on knowledge of adaptive genetic variation to current climatic conditions. Traditional methods for identifying and quantifying localized adaptation through reciprocal transplants and/or common garden experiments have been challenging and often infeasible for many wild non-model organisms because of experimental difficulties, long generation times, or other challenges in obtaining phenotypic traits associated with fitness. With advances in genomic technology, it is now less expensive to generate population genomic data that can be used as a complementary strategy for examining local adaptation across the entire distribution of a target species. Although millions of variants may exist in the genome of any given species, only some of these are expected to be relevant to climate adaptation.

Fig. 1. Population structure and gene-environment associations in Platycladus orientalis. (Jia et al., 2020)

Solutions Offering at CD Genomics

Climate and environmental change are having a major impact on Earth's ecosystems and the species they inhabit. Understanding how organisms adapt to these changes is critical to effective conservation and management strategies. CD Genomics is at the forefront of utilizing long read sequencing technology to study the effects of climate change and environmental change on the genetic makeup of species. Our long read sequencing generates high-quality whole genome sequences, transcriptomes, and epigenomes, providing the fine-grained information needed to assess the adaptive capacity of species.

• Whole Genome Sequencing

We offer specialized whole genome sequencing for species' ability to adapt to climate and environmental change. By obtaining the complete DNA sequence of an organism's genome, we can analyze genetic variations and mutations that may contribute to its adaptive potential. Whole genome sequencing allows us to identify specific genes and genetic pathways associated with adaptation to changing environments.

• Transcriptomics Analysis

CD Genomics also utilizes transcriptomics to study gene expression patterns and identify changes in gene activity in response to climate change and environmental challenges. By analyzing the full set of RNA molecules produced by an organism's genes, we can reveal the molecular mechanisms of adaptation.

• Epigenomics Analysis

We offer epigenomics to analyze the chemical modifications that occur on DNA and its associated proteins that affect gene expression without altering the underlying DNA sequence. By studying epigenetic changes, we help you analyze how environmental factors affect gene regulation and influence adaptation.

Advantages of Our Long Read Sequencing Solutions for Climate and Environment Change

• Comprehensive genomic insights, the combination of multiple approaches allows us to study genetic variation, gene expression patterns, and epigenetic modifications to gain a comprehensive understanding of how organisms respond to climate change and environmental change.
• Fine-grained patterns of local adaptation are addressed by identifying climate related genetic variation and understanding species adaptation to climate change.
• Changes in species ranges over time can be modeled, providing novel insights for assessing evolutionary adaptive potential and predicting disruptions in local adaptation and species vulnerability in the face of climate change.

CD Genomics is committed to advancing genomics research and providing innovative solutions to the challenges posed by climate change and environmental change. We aim to help you understand the molecular mechanisms by which species adapt to change and guide the conservation of Earth's biodiversity in a rapidly changing world. If you have any questions, please feel free to contact us. We look forward to working with you on projects of interest.

Related Services

PacBio SMRT Sequencing
Oxford Nanopore Sequencing
Animal/Plant Whole Genome Sequencing
Transcriptomics with Long-Read Sequencing
Epigenetics and Methylation Analysis Using Long-Read Sequencing