Viral Vector Development Solutions

Overview of sequencing in viral vector development

Overview of sequencing in gene therapy researchA viral vector uses a modified virus as a drug delivery vehicle to introduce specific DNA sequences - encoding genes, regulatory RNA (e.g., small interfering RNAs) or other substrates - into cells. This technology has long been of interest because of its potential advantages over traditional approaches. Many types of agents (e.g., enzymes, antibodies, and siRNAs) can be encoded in DNA sequences that can be rapidly designed and synthesized once the target is identified. Viruses can serve as powerful delivery vehicles for genes because of their ability to enter cells efficiently and potentially into hard-to-reach, highly specific cells. Based on this, viral vector can be used to modify gene expression in a programmable manner, providing the flexibility to potentially treat a wide range of diseases.

Sequencing is an important tool in the viral vector design process and payload validation process, such as AAV genome integrity checks, heterogeneity assays, AAV vector design and improvement, and lentiviral integration site analysis. For more in-depth research and advancement, CD Genomics provides you with one-stop NGS-based viral vector development solution and integration site analysis services. The entire sequencing process is maintained under strict QC standards to ensure reliable data support for your research.

Viral vector development solutions from CD Genomics

CD Genomics' goal has always been to provide high quality NGS-based solutions to global pharmaceutical and biotech companies. Viral vector delivery system (mainly AAV and lentivirus vectors) has shown great promise in genetic diseases and rare diseases, and our sequencing service solutions are dedicated to advancing research. We are always adding scalability to the sequencing field, and we always hope that our viral vector research solutions will provide you with more ideas, inspiration and assistance. CD Genomics' viral vector development solutions provide not only NGS sequencing services for viral vectors, but also a range of analytical services from viral vector development and design, identity verification, to evaluation and quality control.

Lentiviral Integration Sites Analysis

Lentiviral Integration Sites Analysis

CD Genomics can provide you with NGS-based lentiviral integration site analysis services, enabling specific capture of integration site sequences and comprehensive bioinformatics analysis. The entire process of lentiviral integration site analysis follows strict QC standards to ensure the highest quality data and reliable data analysis reports for you. Lentiviral integration site analysis is an important tool for the identification of integration sites and the study of integration mechanisms in viral gene therapy, as well as for the avoidance of viral integration side effects. We are also always committed to provide you with higher quality and more reliable sequencing services.

AAV Sequencing

AAV Sequencing

CD Genomics' goal has always been to provide the highest quality NGS-based standardized AAV sequencing to be your right-hand man in AAV gene therapy research. Our AAV sequencing services and solutions focus on these areas, such as AAV whole genome sequencing, AAV-ITR sequencing, AAV expression quantification and host response assay analysis. The main processes of AAV sequencing are as follows, including AAV sample preparation, AAV library preparation, up-sequencing and bioinformatics analysis. Our sequencing process is governed by strict quality control standards, ultimately ensuring the most reliable data analysis reports for you with the fastest turnaround time.

We are convinced that CD Genomics is the partner you have been seeking for viral vector gene delivery development. Our automated sequencing platform and dedicated team of experts guarantee the accuracy of sequencing and analysis results. If you are interested in our solution, please feel free to contact us.

For research use only, not intended for any clinical use.


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