Thank you for visiting the CD Genomics Blog! Here, you will find articles on the latest advances in sequencing technology, biotech research developments, and technical introductions. Our blog helps researchers and professionals deepen their understanding and stay updated on industry trends.
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With the advent of the post-genome era, gene chip and next-generation sequencing have become two important branches of biochemistry and molecular biology technologies. DNA microarray, also known as gene chip, is a method characterized by high throughput, high efficiency, and high automation. In a gene chip array, a large number of known probe sequences are […]
In the past decade, second-generation sequencing has been rapidly developed and widely used in the studies of genome, transcriptome, and epigenetics of many species. It also acts as an important technological support for pharmacy, diagnosis, and many other fields. In recent years, second-generation sequencing has been increasingly used to monitor protein translation. Combining ribosome profiling […]
Microbial ecology is the study of the relationships of microorganisms with one another and with their environment. Microbial diversity, distribution, abundance, specific interactions, and their impact on ecosystems are explored. Elected by the scientific journal Nature as one of the technologies to watch for in 2020, single-cell sequencing is a rising technology in single-cell ecology. […]
The transcriptome is the collection of all RNA transcribed by an individual or a population of cells at a certain biological state. The studies into transcriptome focus on mRNAs and non-coding RNAs (ncRNAs), which encode various proteins and act as cellular regulators respectively. Transcriptomic studies interpret gene function and gene structure in a holistic view, […]
Emerging infectious diseases have the potential to impose enormous mortality, morbidity, and economic burdens on humans. Tracking the spread of infectious diseases to help control them has traditionally relied on the analysis of case data collected during the course of an epidemic or pandemic. Over the last few decades, there has been a few cases […]
What Is DNA Sequencing? DNA sequencing refers to the method employed to determine the order of the four nucleotide bases—adenine, thymine, cytosine, and guanine—that constitute a DNA molecule and convey critical genetic information. Within the DNA double helix, these four bases pair with specific partners to form units known as base pairs (bp): adenine (A) with […]
What Is Sanger Sequencing? Sanger sequencing, also known as the “chain termination method,” was developed by the English biochemist Frederick Sanger and his colleagues in 1977. This method is designed for determining the sequence of nucleotide bases in a piece of DNA (commonly less than 1,000 bp in length). Sanger sequencing with 99.99% base accuracy […]
What Is mRNA? Messenger RNAs (mRNAs) are single-stranded molecules in cells that transfer genetic information from the DNA in the nucleus to the cytoplasm, where proteins are synthesized (in the ribosomes). mRNAs are a group of RNAs that can be translated into proteins, while other RNAs cannot. Because nearly every function in the organisms is […]
What Is Sanger Sequencing? Sanger sequencing, also known as the “chain termination method” was developed by the British biochemist Frederick Sanger and his colleagues in 1977. This method is designed for determining the sequence of nucleotide bases in a piece of DNA (commonly less than 1,000 bp in length). Sanger sequencing with 99.99% base accuracy […]
Amplicons Definition In molecular biology, amplicons represent DNA or RNA fragments that are the source and/or product of amplification or replication events. They can be naturally formed through gene duplication. Natural gene duplication plays a crucial role in genomic evolution. In this context, an amplicon refers to a section of chromosomal DNA that has been […]
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