What Is mRNA? Messenger RNAs (mRNAs) are single-stranded molecules in cells that transfer genetic information from the DNA in the nucleus to the cytoplasm, where proteins are synthesized (in the ribosomes). mRNAs are a group of RNAs that can be translated into proteins, while other RNAs cannot. Because nearly every function in the organisms is […]
What Is Sanger Sequencing? Sanger sequencing, also known as the “chain termination method” was developed by the British biochemist Frederick Sanger and his colleagues in 1977. This method is designed for determining the sequence of nucleotide bases in a piece of DNA (commonly less than 1,000 bp in length). Sanger sequencing with 99.99% base accuracy […]
This is a review of lncRNA research in plants, which mainly describes the IncRNA regulation mechanism in siRNA mediated transcriptional gene silencing. There are two main ways: first, as siRNA precursor; second, activation of Long non-coding RNA transcription can help siRNA identify its target sites, which is involved in siRNA mediated DNA methylation. In addition, […]
Exon is a part of eukaryotic genome sequence. The exome is the total of all exons, which takes one percent in the whole genome sequence of human beings. The exome sequencing is to capture and enrich the exome in the whole genome sequence by targeted capture, and get the genomic information by next generation sequencing. […]
Ribose Nucleic Acid, also named RNA, is the intermediary of DNA and protein. Compared with DNA, RNA has less molecular-weight but more classification.With the development of all kinds of research, scientists found that RNA plays an important role in the evolution of life. I hope this article can share basic knowledge with you and can […]
Lnc RNA, also known as the long non-coding RNA, is a kind of RNA with over 200nt transcript which do not encode protein. It was judged as a “noise” in transcriptomics until 2007, but now well-known as it’s ability of regulating gene expression on transcription, epigenetic and post-transcriptional regulation. And it is related to many […]
The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, as well as other non-coding RNA produced in one or a population of cells. It is different from the exome because it includes only those RNA molecules found in a specified cell population, and usually includes the amount or concentration of each […]
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