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Virus Sequencing: Technologies, Features, and Significance in Outbreaks

Virus Sequencing: Technologies, Features, and Significance in Outbreaks

Emerging infectious diseases have the potential to impose enormous mortality, morbidity, and economic burdens on humans. Tracking the spread of infectious diseases to help control them has traditionally relied on the analysis of case data collected during the course of an epidemic or pandemic. Over the last few decades, there has been a few cases […]

Amplicons and Amplicon Sequencing

Amplicons and Amplicon Sequencing

Amplicons Definition In molecular biology, amplicons represent DNA or RNA fragments that are the source and/or product of amplification or replication events. They can be naturally formed through gene duplication. Natural gene duplication plays a crucial role in genomic evolution. In this context, an amplicon refers to a section of chromosomal DNA that has been […]

Fact Sheet: Genome, DNA, RNA

Fact Sheet: Genome, DNA, RNA

What is a genome? A genome is the complete set of DNA (or RNA in RNA viruses) of an organism. It is sufficient to build and maintain that organism. Each nucleated cell in the body contains this same set of genetic material. In humans, a copy of the entire genome consists of more than 3 […]

Genomics—Forensic Age Identification

Genomics—Forensic Age Identification

Summary: a DNA methylation age inference method, combined with Sequenom MassARRAY technology, can reduce the error of the age to 4.7 years. Age estimation is one of the most important topics in the field of forensic medicine. Especially for juvenile delinquency, highly corrupt bones of the dead and nameless corpse, it can provide the scope […]

Three Companies for Exome Capture Efficiency Evaluation

Three Companies for Exome Capture Efficiency Evaluation

Whole exome sequencing (WES) is now being used more and more in the field of research and diagnosis. Researchers are expected to study the entire coding regions of known genes with adequate sequencing depth and coverage. Currently a large number of exome capture platforms on the market have there respective advantages and some differences in […]

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